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KMID : 0621520120170030137
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Journal of the Korean Society for Surgery of the Hand
2012 Volume.17 No. 3 p.137 ~ p.141
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Ischemic Necrosis of the Upper and Lower Extremities after the Use of Norepinephrine
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Kim Seong-Hun
Kim Seong-Ki
Roh Si-Gyun
Lee Nae-Ho
Yang Kyung-Moo
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Abstract
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Purpose: Norepinephrine is initially used to increase blood pressure in patients with septic shock. It increases blood flow to vital organs but decrease the flow to end-organs resulting in ischemic changes in end-organs. We report five
patients with ischemic necrosis of upper and lower extremities after using norepinephrine in septic shock.
Materials and Methods: We retrospectively reviewed medical record of five patients with ischemic necrosis of upper and lower extremities after treating septic shock from March 2010 to March 2011.
Results: Five patients developed ischemic necrosis of upper and lower extremities during intensive care. All patients experienced septic shock due to medical problems, which required norepinephrine to increase blood pressure. After conservative treatment, stump revision or below knee amputation were done.
Conclusion: We believe that more active treatment and protection of the end-organs will be needed to prevent poor prognosis during the recovery of septic shock.
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KEYWORD
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Upper extremity, Lower extremity, Necrosis, Norepinephrine, Septic shock
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